Sodium Aescinate

Sodium Aescinate 
Sodium Aescinate CAS: 20977-05-3            Molecular Weight：1124.233  Formula：C54H84NaO23+
Purity:                  HPLC98%
Appearance：     Powder
Test Method：    HPLC; Mass;NMR
Usage:                 For laboratory research use only,not for human or diganostic use。
Package              20mg~1g per bottle。
Storage：           Store in a well closed container, protected from air and light.
Prepare and use solutions at the time of testing. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

Plant Origin
Aesculus chinensis

Description
SA treatment could alleviate the symptom of PCOS in rat model through regulating the PI3K/Akt/GSK3-β pathway (Fig. 4, Ref. 22).[1] Sodium aescinate inhibit the proliferation and induce apoptosis in the gastric cancer BGC-823 cells and AGS cells, and this process can be implemented by inhibiting the JAK-1/STAT-1 signaling pathway.[2]

References

[1]. Chen L et al.Effect of sodium aescinate treatment on PCOS rat model with insulin resistance.Format: AbstractSend to Bratisl Lek Listy. 2017;118(4):223-227.

[2]. Sodium Aescinate Induced Apoptosis of BGC-823 and AGS Cells by Inhibiting JAK-1/STAT-1 Signaling Pathway.Zhong Yao Cai. 2016 Sep;39(9):2086-90.

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